Table 1 Study schedule of data collection and assessments

Consent

X

Randomisation

X

Baseline data (defined)

X

 Montreal Cognitive Assessment [31]

X

X

X

 Cogstate [32]

X

X

X

 Confusion Assessment Method [33]

X

X

X

 Tolerability of Low Temperature Dialysis Questionnaire

Every 2 weeks for the first 6 weeks

 Assessment of QoL [34]

X

X

X

 Bristol Activities of Daily Living Scale [35]

X

X

X

 Carer burden assessment [36]

X

X

X

 Hospital Anxiety and Depression Scale [37]

X

X

X

 HD recovery time [38]

X

X

X

 Qualitative interview

At completion or drop out

Dialysis temperature recording

Physiological measurements*

Laboratory measurements**

Adverse event reporting

X

X

X

Review Concomitant Medications

X

X

X