n | Intervention | Control | |
---|---|---|---|
Group sizea | 111 | 56 (50) | 55 (50) |
Reason for study completion | 110 | ||
Removed | 41 (75) | 42 (76) | |
Patient transferred | 6 (11) | 7 (13) | |
4 weeks completed | 7 (13) | 5 (9) | |
Patient deceased | 1 (2) | 1 (2) | |
Reason for removalb | 83 | ||
tx completed, no device complications | 27 (66) | 29 (69) | |
tx incomplete, device complications | 12 (29) | 11 (26) | |
tx completed, device complications | 1 (2) | 1 (2) | |
Transferred, no device complications | 1 (2) | 1 (2) | |
Complications (resulting in failure)c | |||
Any complication | 110 | 13 (24) | 12 (22) |
PICC-associated BSI, suspected | 25 | 6 (46) | 5 (42) |
Dislodgement, full | 25 | 4 (31) | 7 (58) |
Occlusion | 25 | 3 (23) | 1 (8) |
Skin reaction | 25 | 1 (8) | 0 (0) |
Fracture | 25 | 0 (0) | 0 (0) |
Suspected thrombus | 25 | 0 (0) | 0 (0) |
Complications (during tx)c | |||
Any complication | 110 | 25 (45) | 20 (36) |
Occlusion | 45 | 15 (60) | 11 (55) |
PICC-associated BSI, suspected | 45 | 8 (32) | 3 (15) |
Dislodgement, partial | 45 | 7 (28) | 4 (20) |
PICC-associated thrombosis, suspected | 45 | 1 (4) | 1 (5) |
Other | 45 | 4 (16) | 3 (15) |
Serious adverse eventsc | |||
Any type | 110 | 5 (9) | 6 (11) |
Positive blood culture | 11 | 3 (60) | 3 (50) |
Unplanned admission to ICU | 11 | 2 (40) | 2 (33) |
Death | 11 | 1 (20) | 2 (33) |
Infection (baseline or during tx)c | |||
Any type | 110 | 45 (82) | 37 (67) |
Wound | 82 | 14 (31) | 12 (32) |
Urinary | 82 | 8 (18) | 9 (24) |
Bone | 82 | 4 (9) | 7 (19) |
Faecal/gastrointestinal | 82 | 7 (16) | 3 (8) |
Respiratory | 82 | 5 (11) | 4 (11) |
Skin/cellulitis | 82 | 7 (16) | 1 (3) |
Other | 82 | 11 (24) | 13 (35) |
Unknown | 82 | 4 (9) | 5 (14) |
Confirmed BSI classifications (count)c | |||
LCBI (common commensal) | 110 | 3 (5) | 0 (0) |
CLABSI | 110 | 0 (0) | 2 (4) |
MBI-LCBI | 110 | 1 (2) | 0 (0) |
Thrombus, confirmed | 110 | 1 (2) | 0 (0) |
Pain at removal (0 = worst, 10 = none)d | 26 | 0.0 (0–0) | 0.0 (0–0) |
Outpatient/HITH tx | 110 | 19 (35) | 14 (25) |