From: An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus streptomycin + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial
Variables
Timing (days)
1
2
3
4
5
6
7
8
9
10
11
21+/−2
M3
RDT Bubo/sputum
X
PCR Bubo/sputum
Bubo/sputum culture
Plague serology
X*
Malaria Ag