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Table 2 Continuous feeding protocol (control group)

From: Protein delivery in intermittent and continuous enteral nutrition with a protein-rich formula in critically ill patients—a protocol for the prospective randomized controlled proof-of-concept Protein Bolus Nutrition (Pro BoNo) study

Time

06:00–11:00

11:00–12:00

12:00–17:00

17:00–18:00

18:00–23:00

23:00–00:00

00:00–05:00

05:00–06:00

Nutrition

Break + GRV

Nutrition

Break + GRV

Nutrition

Break + GRV

Nutrition

Break + GRV

Day 1

 Protein dose1

0.05

 

0.1

 

0.2

 

0.3

 

 Flow rate2

5–9

 

10–18

 

20–36

 

30–54

 

 Total protein3

0.05

0.15

0.35

0.65

Day 2

 Protein dose1

0.4

 

0.4

 

0.4

 

0.4

 

 Flow rate2

40–72

 

40–72

 

40–72

 

40–72

 

 Total protein3

1.0

1.3

1.5

1.6

  1. GRV gastric residual volume
  2. 1[g/kgBW/5 h], 4 nutrition cycles/24 h: each with 5 h nutrition followed by a 30-min break and 30 min GRV measure, no night time break. Total time of feeding, 20 h; GRV measurements, 2 h; break 2 h
  3. 2[ml Fresubin© Intensive/h], depending on bodyweight
  4. 3Total of administered protein of the preceding 24 h [g/kgBW]