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Table 2 Definition of clinical stability (Halm et al. 1998) [14]

From: Effect of albumin administration on outcomes in hypoalbuminemic patients hospitalized with community-acquired pneumonia (ALBUCAP): a prospective, randomized, phase III clinical controlled trial—a trial protocol

• Temperature ≤ 37.8 °C without antipyretic agents

• Heart rate ≤ 100 per minute

• Spontaneous respiratory rate ≤ 24 per minute

• Systolic blood pressure ≥ 90 mmHg without vasopressor support

• Adequate oxygenation on room air (PaO2 ≥ 60 mmHg or pulse oximetry ≥ 90%)a

  1. aFor patients with chronic hypoxemia or chronic oxygen therapy, PaO2, or pulse oximetry measurement, must be back to baseline