Skip to main content

Table 1 Glucocorticoid therapy protocol in each group

From: Vestibular prognosis in idiopathic sudden sensorineural hearing loss with vestibular dysfunction treated with oral or intratympanic glucocorticoids: a protocol for randomized controlled trial

 

Drug

Protocol

Group 1

Pred.

Glucocorticoid therapy:

d1–d7: Oral Pred. 1 mg/kg/d (maximum daily dosage is no more than 60 mg)

d8–d9: Oral Pred. 10 mg less than d7

d10–d11: Oral Pred. 10 mg less than d9

d12: Oral Pred. 10 mg less than d11

d13: Oral Pred. 10 mg less than d12

d14: Oral Pred. 10 mg less than d13a

Group 2

Met.

Glucocorticoid therapy:

One intratympanic injection of 40 mg/ml Met. at d1, d3, d5, d7, d9, d11, and d13;b

  1. Pred. prednisone, Met. methylprednisolone, d. day
  2. aIf the patient’s weight is less than 50 kg, the administration will be stopped after the day with < 10 mg prednisone administered, for example, a patient weighs 45 kg will stop receiving glucocorticoids at the 13th day
  3. bOne day early or late of injection is allowed for practicality