Table 2 Study design schedule in accordance with the Standard Protocol Items: Recommendations for interventional Trials (SPIRIT). MACCE major adverse cardiac and cerebral events, ADAS-cog Alzheimer’s Disease Assessment Scale and cognitive subscale, MMSE Mini Mental State Examination, IADL Instrumental Activities of Daily Living, PostopQRS Postoperative Quality of Recovery Scale, FDQ Functional Difficulties Questionnaire, FSST Four Square Step Test