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Table 1 Schedule of assessments

From: TILT: Time-Lapse Imaging Trial—a pragmatic, multi-centre, three-arm randomised controlled trial to assess the clinical effectiveness and safety of time-lapse imaging in in vitro fertilisation treatment

 

Baseline

Day of egg collection (D0)

Day of fertilisation check (D1)

Days 3, 5 and optionally day 6

Routine visit to fertility unit approx. 2 weeks after embryo transfer

Approx. 8 weeks of gestation

Approx. 24 weeks of gestation

Approx. 6 weeks after the expected due date

Informed consent

X

       

Confirmation of informed consent

 

X

      

Baseline demographic and clinical data

X

       

Randomisation and confirmation to randomised participants

  

X

     

Ineligible consented participants informed

  

X

     

Embryo grading; transfer if appropriate

   

X

    

Documentation of morphokinetic parameters (arm 1 only)

   

X

    

Pregnancy test outcome

    

X

   

Elective single embryo transfer rate

    

X

   

Clinical pregnancy rate

     

X

  

Multiple pregnancy rate

     

X

  

Miscarriage rate

      

X

 

Live birth rate

       

X

Stillbirth rate

       

X

Multiple birth rate

       

X

Serious adverse events

  

X

 

X

X

X

X