Table 1 Definition of the 5 candidate biomarker signatures and estimated prevalences with included biomarker subgroup combinations, in the order AR, DRD, TP53, and TEfus (where “+” indicates mutated, “−” wild-type/non-mutated)
Signatures | − | −−−+ | −−+− | −−++ | −+−− | −+−+ | −++− | −+++ | +−−− | +−−+ | +−+− | +−++ | ++−− | ++−+ | +++− | Prev |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
All | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 1 |
TP53− and AR− | x | x | x | x | 0.5 | |||||||||||
TP53+ | x | x | x | x | x | x | x | 0.37 | ||||||||
DRD+ | x | x | x | x | x | x | x | 0.19 | ||||||||
TEfus+ | x | x | x | x | x | x | x | 0.32 |