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Fig. 3 | Trials

Fig. 3

From: A novel method for interpreting survival analysis data: description and test on three major clinical trials on cardiovascular prevention

Fig. 3

Pharmaco-economic indices MoT/y+ and NNT/y+ for PROVE-IT (4p-MACE*), LIFE (3p-MACE) and HOPE (3p-MACE) trials. a Observed (continuous green lines) Months of treatment per 1 year gained (MoT/y+) curves throughout the three trial and estimated MoT/y+(eMoT/y+; dotted green lines) up to time 72 months. The arrows show the time at which the 50% of the cohort was in follow-up for PROVE-IT and LIFE trial and the 50% of the duration of the study for the HOPE trial. b Observed (continuous red lines) number needed to treat per 1 year gained (NNT/y+) curves throughout the three trial and estimated NNT/y+ (eNNT/y+; dotted red lines) curves up to time 72 months. The arrows show the time at which the 50% of the cohort was in follow-up for PROVE-IT and LIFE trial and the 50% of the duration of the study for the HOPE trial

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Trials

ISSN: 1745-6215