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Table 1 Schedule of the study process (SPIRIT Figure)

From: Efficacy and safety of Dingkun pill for female infertility patients with low prognosis undergoing in vitro fertilization-embryo transfer: study protocol for a multicenter, double-blind, randomized, placebo-controlled trial

 Study period
EnrollmentAllocationPost allocation
Timepoint*1st visit0 week1–6 weeks7–12 weeks4–6 months
Enrollment:
 Eligibility screen    
 Informed consent    
 Allocation by TCM team    
Interventions:
 DKP treatment    
 Placebo treatment    
Assessments:
 Basic ovarian reserve test (AFC, bFSH, AMH, etc.)    
 Laboratory index measurement (oocyte, zygote, embryo, etc.)    
 Pelvic ultrasound evaluation (endometrium thickness and classification)    
 IVF pregnancy outcome    
 Liver and renal function assessment