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Table 1 The schedule of treatments and data collection

From: Efficacy of chloroquine versus lopinavir/ritonavir in mild/general COVID-19 infection: a prospective, open-label, multicenter, randomized controlled clinical study

  1. The SOFA (Sequential Organ Failure Assessment) score predicts mortality risk for patients in the intensive care unit based on laboratory results and clinical data1
  2. Coagulation index: PT prothrombin time, APTT activated partial prothrombin time, Fib fibrinogen, D-Dimer D-dimer, PLT platelet count
  3. Inflammatory factors: various cytokines involved in inflammation, such as interleukin (IL)-6, IL-10, tumor necrosis factor (TNF)-α, etc.
  4. PCT (procalcitonin): a protein that increases when severe bacterial, fungal, and parasitic infections, sepsis, and multiple organ failure occur
  5. − D0: before the research; D0: start of the research; D1: 1st day of the research; D2: 2nd day of the research; D3: 3rd day of the research; D4: 4th day of the research; D5: 5th day of the research; D6: 6th day of the research; D7: 7th day of the research; D10: 10th day of the research; D14: 14th day of the research; D21: 21st day of the research; D28: 28th day of the research; D29: after the research
  6. References:
  7. 1 Medlej K. Calculated decisions: sequential organ failure assessment (SOFA) score. Emerg Med Pract 2018;20:CD1-CD2.