Table 1 REOX trial inclusion and exclusion criteria

• Patients over 18 years of age

• Patients with leg ulcers (venous, ischaemic, traumatic or diabetic foot ulcer)

• Patients with dehisced surgical wounds healing by second intention

• Patients with pressure ulcers

• Wound area between 1 and 250 cm² (wounds larger than 250 cm² are very unusual and outside the scope of this kind of treatment and therefore we decided to exclude it since such a large wound could be more difficult to heal)

• Systemic inflammatory disease or oncological disease

• Wounds with clinical signs of infection

• Terminal situation (life expectancy less than 6 months)

• Ulcers from other aetiologies: tumours, infectious

• Wounds treated with negative pressure therapy

• Pregnancy

• History of sensitivity or allergy to any of the components of the study dressing