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Table 1 Key characteristics of included case studies and trials

From: Evidencing the impact of cancer trials: insights from the 2014 UK Research Excellence Framework

Case studies (n = 46)

Number

Percentagec

Research Excellence Framework (REF) impact typea

 Health

37

80%

 Technological

8

17%

 Political

1

2%

REF Unit of Assessmentb

 Clinical Medicine

38

83%

 Public Health, Health Services and Primary Care

4

9%

 Allied Health Professions, Dentistry, Nursing and Pharmacy

2

4%

 Psychology, Psychiatry and Neuroscience

1

2%

 Biological Sciences

1

2%

Trials (n = 110)d

Trial focus

 Treatment of cancer or its side effects

97

88%

 Screening

6

5%

 Diagnosis

4

4%

 Other (e.g. large observational trial to investigate cancer incidence)

3

3%

Phase of trial

 I

17

15%

 II

14

13%

 III

75

68%

 Unknown/other

4

4%

Higher-education institution (n = 19)

 University College London

9

20%

 Institute of Cancer Research

4

9%

 University of Leeds

4

9%

 University of Manchester

4

9%

 Queen Mary University of London

4

9%

 Imperial College London

3

7%

 University of Cardiff

2

4%

 University of Edinburgh

2

4%

 University of Glasgow

2

4%

 University of Nottingham

2

4%

 University of Oxford

2

4%

 University of Birmingham

1

2%

 University of Bradford

1

2%

 University of Bristol

1

2%

 Cardiff University

1

2%

 University of Cambridge

1

2%

 King’s College London

1

2%

 Newcastle University

1

2%

 University of Southampton

1

2%

Diagnoses of patients recruited to the included clinical trials (n = 110)d

 Breast

38

35%

 Gastrointestinal (lower)

15

14%

 Haematological

15

14%

 Urological

13

12%

 Gynaecological

10

9%

 Thorax

8

7%

 Central nervous system

4

4%

 Head and neck (including thyroid)

3

3%

 Multiple cancer types

3

3%

 Gastrointestinal (upper)

1

1%

Main source of clinical trial funding (n = 110)d

 Industry only

33

30%

 Charity and Research Council/Government/University

19

17%

 Research Council/Government/University only

16

15%

 Unknown

14

13%

 Charity and Industry

13

12%

 Charity, Industry and Research Council/Government/University

8

7%

 Charity only

7

6%

  1. aThe Summary Impact Types are eight categories of impact, assigned to each case study by text analysis after submission to the REF. These categories are technological, economic, health, political, legal, cultural, societal and environmental
  2. bThe Units of Assessment are 36 subject areas, each with its own REF expert review panel. These subject areas are divided into four main panels which group similar research disciplines. For example, Panel A includes Clinical Medicine and Biological Sciences, Panel B: Chemistry and Physics, Panel C: Law and Economics, and Panel D: History, Classics and Languages. Each discipline listed within these main panels represents one Unit of Assessment
  3. cMay not add to 100% due to rounding
  4. dEach clinical trial (n = 106) was counted for each individual case study in which it was mentioned (a total of 106 trials mentioned in separate case studies 110 times)