Inclusion criteria | |
 Aged between 18 and 80 years | |
 Reflux in the great saphenous vein of > 0.5 s | |
 Diameter of the saphenous vein between 2 and 20 mm (standing position) | |
 One or more of the symptoms related to the incompetent saphenous vein | |
 CEAP classification of C2 through C5 | |
Exclusion criteria | |
 Previous treatment in the targeted vein segment | |
 Tortuous vein in which the delivery catheter cannot be inserted | |
 Aneurysm of target-vein segment of > 20 mm | |
 Daily use of narcotic or pain medications to control pain associated with reflux | |
 Known hypercoagulable disorder | |
 Active malignancy | |
 Regular or current use of systemic anticoagulation | |
 Previous deep vein thrombosis/pulmonary embolism or active acute superficial thrombophlebitis | |
 Unable to comply with the schedule and protocol evaluations | |
 Unable to ambulate | |
 Unable to provide informed consent | |
 Currently pregnant or breastfeeding | |
 Known sensitivity to cyanoacrylate adhesives | |
 Participation in another clinical study that did not reach the primary endpoint within 30 days prior to enrollment |