NUrse-led COntinuum of care for people with Diabetes and prediabetes (NUCOD) in Nepal: study protocol for a cluster randomized controlled trial

Table 2 Measures of outcome variables

	Assessment method	Assessor	Baseline	Midline (6 months)	End line (12 months)	Variable
Clinical outcomes
Primary outcome
Glycemic control (HbA1c)^a for diabetes	Blood sample	Biochemist	x	x	x	Continuous
Incidence of diabetes among prediabetes	EHR	RA/nurse		x	x	Binary
Secondary outcomes
Blood pressure	Electronic monitor	RA/nurse	x	X	x	Continuous
Lipid profile	Blood sample	Biochemist	x	X	x	Continuous
Body mass index	EHR^b	RA/nurse	x	x	x	Continuous
Implementation outcomes
Reach	Log record^c	RA/nurse		x	x	Continuous
Adoption	SDSCA/DTSQ	RA/nurse	x	x	x	Binary
Implementation (fidelity)	Checklist	SP		x	x	Continuous
Self-monitoring of glucose	Self-reported	RA/nurse		x	x	Binary
Medication adherence	Self-reported	RA/nurse		x	x	Binary

DTSQ Diabetes Treatment Satisfaction Questionnaire, EHR electronic health record, HbA1c hemoglobin A1c (aka glycated hemoglobin), RA research assistant, SDSCA Summary of Diabetes Self-Care Activities Assessment, SP standardized patient
^aThe average level of blood sugar over the past 2–3 months
^bCalculated as weight in kilograms divided by height in meters squared
^cNumber of people participating in the program divided by the number of people eligible to be recruited into the program

ISSN: 1745-6215