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Table 1 Patient inclusion and exclusion criteria for the CAST-HF trial

From: Safety and efficacy of direct Cardiac Shockwave Therapy in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting (the CAST-HF trial): study protocol for a randomized controlled trial

Inclusion criteriaExclusion criteria
• Male or female patients above 21 years and under 90 years of age
undergoing primary coronary artery bypass grafting
• Patients must present with reduced left-ventricular function defined as LVEF ≤ 40%
• Patients must present with regional left-ventricular-wall-motion abnormalities
• Patients have to give written informed consent to participate in the study
• Significant concomitant aortic valve disease in need of surgical
treatment (except significant aortic valve disease not detected in preoperative cardiac ultrasound that is detected intra-operatively)
• Serious radiographic contrast allergy
• Patients in cardiogenic shock
• Patients with contraindication for cardiac MRI
• History of significant ventricular arrhythmias, except arrhythmias
associated with MI
• Present co-morbidity which reduces life expectancy to less than 1
year
• Presence of a ventricular thrombus
• Presence of a cardiac tumor
• Pregnancy
  1. Key: LVEF left ventricular ejection fraction, MI myocardial infarction, MRI magnetic resonance imaging