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Table 1 Characteristics of the participants at baseline according to BP-control group

From: Achieving blood pressure control targets in hypertensive patients of rural China – a pilot randomized trial

 TotalA Standard
(140 ~ < 150 mmHg)
B Moderate
(130 ~ < 140 mmHg)
C Intensive
(< 130 mmHg)
P value*
Number105353535 
Age (years)
 Overall68.4 ± 5.567.4 ± 4.968.2 ± 5.869.5 ± 5.80.259
 ≥ 75 years of age17 (16.2%)3 (8.6%)6 (17%)8 (22.9%) 
Baseline blood pressure (mmHg)
 Systolic149.6 ± 11.6146.7 ± 8.6147.2 ± 7.0150.6 ± 8.50.098
 Diastolic89.2 ± 9.787.3 ± 9.188.5 ± 9.589.7 ± 10.60.581
BMI26.5 ± 3.425.8 ± 3.326.9 ± 3.826.8 ± 3.10.346
Sex    1
 Male33 (31.4%)11 (31.4%)11 (31.4%)11 (31.4%) 
 Female72 (68.6%)24 (68.6%)24 (68.6%)24 (68.6%) 
Smoking status    0.446
 Never84 (80.0%)27 (77.1%)27 (77.1%)30 (85.7%) 
 Former12 (11.4%)6 (17.1%)3 (8.6%)3 (8.6%) 
 Current9 (8.6%)2 (5.7%)5 (14.3%)2 (5.7%) 
Diabetes history16 (15.2%)6 (17.1%)3 (8.6%)7 (20.0%) 
Distribution of systolic blood pressure (number %)    0.143
 > 150 mmHg43 (41.0%)11 (31.4%)12 (34.3%)20 (57.1%) 
 > 140 ≤ 150 mmHg48 (45.7%)17 (48.6%)19 (54.3%)12 (34.3%) 
 > 130 ≤ 140 mmHg14 (13.3%)7 (20.0%)4 (11.4%)3 (8.6%) 
Antihypertensive drug use1.41.41.41.50.923
Other medication usage
 Statins6 (5.7%)1 (2.9%)3 (8.6%)2 (5.7%) 
 Aspirin21 (20.0%)6 (17.1%)7 (20%)8 (22.9%) 
Laboratory results
 Glucose (mmol/L)6.5 ± 1.76.7 ± 1.86.4 ± 2.06.3 ± 1.30.559
 Cholesterol (mmol/L)5.5 ± 1.55.1 ± 1.85.6 ± 1.05.8 ± 1.50.103
 Triglycerides (mmol/L)1.8 ± 1.52.0 ± 2.21.7 ± 1.11.8 ± 0.90.575
 LDL (mmol/L)4.1 ± 0.93.9 ± 0.94.0 ± 0.94.3 ± 0.90.307
 HDL (mmol/L)1.5 ± 0.31.5 ± 0.31.5 ± 0.31.5 ± 0.30.913
 Homocysteine (μmol/L)10.4 ± 2.610.6 ± 3.29.9 ± 1.910.5 ± 2.70.496
MTHHR C677T    0.679
 CC24 (22.9%)7 (20.0%)7 (20.0%)10 (28.6%) 
 CT52 (49.5%)20 (57.1%)18 (51.4%)14 (40.0%) 
 TT29 (27.6%)8 (22.9%)10 (28.6%)11 (31.4%) 
  1. Data are mean (SD) or number (%)
  2. ACE angiotensin-converting enzyme, ARB angiotensin-II-receptor blocker, BMI body mass index, BP blood pressure, MTHFR methylenetetrahydrofolate reductase, LDL low-density lipoprotein, HDL high-density lipoprotein
  3. *Difference between groups p < 0·0001