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Table 1 Single nucleotide polymorphisms (SNPs) for plant sterol responsiveness testing

From: Genetic basis for prediction of non-responders to dietary plant sterol intervention (GenePredict-PS): a study protocol for a double-blind, placebo-controlled, randomized two-period crossover study

Gene
SNP
Function of geneAssociation with plant sterol response
CYP7A1
rs3808607
The rate-limiting enzyme in the synthesis of bile acid in the classic pathway.T/T = non-responsive
G/T = responsive
G/G = responsive
ApoE
Variant
Apolipoprotein E is a glycoprotein present in human plasma; ApoE is associated with triglyceride-rich lipoproteins (chylomicrons and VLDLs) and HDL.ε2/− = Unknown
ε3/ε3 = neutral
ε4/− = responsive