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Table 1 Single nucleotide polymorphisms (SNPs) for plant sterol responsiveness testing

From: Genetic basis for prediction of non-responders to dietary plant sterol intervention (GenePredict-PS): a study protocol for a double-blind, placebo-controlled, randomized two-period crossover study

Gene

SNP

Function of gene

Association with plant sterol response

CYP7A1

rs3808607

The rate-limiting enzyme in the synthesis of bile acid in the classic pathway.

T/T = non-responsive

G/T = responsive

G/G = responsive

ApoE

Variant

Apolipoprotein E is a glycoprotein present in human plasma; ApoE is associated with triglyceride-rich lipoproteins (chylomicrons and VLDLs) and HDL.

ε2/− = Unknown

ε3/ε3 = neutral

ε4/− = responsive