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Primary analysis: uninformative
|
Sensitivity analyses
|
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Sceptical
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Enthusiastic
|
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Control cure rate
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Beta(4.75, 0.25)
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Beta(4.75, 0.25)
|
Beta(4.75, 0.25)
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Regimen comparison
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N(0, 10,000)
|
N(−0.05, 0.009)
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N(0, 0.009)
|
Strategy comparison
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N(0, 10,000)
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N(−0.1, 0.0036)
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N(0, 0.0036)
|
Ribavirin comparison
|
N(0, 10,000)
|
N(0, 0.009)
|
N(0.05, 0.009)
|
- The beta prior for the control cure rate has mean 0.95 and variance 0.008
- The model will also be adjusted for genotype, which will have the prior N (0, 10,000) in all analyses
- N(m,v) is the normal prior with mean m and variance v