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Fig. 2 | Trials

Fig. 2

From: The design and statistical aspects of VIETNARMS: a strategic post-licensing trial of multiple oral direct-acting antiviral hepatitis C treatment strategies in Vietnam

Fig. 2

Initial probability of stopping groups over an estimated recruitment schedule for various true cure rates. The average true cure rate is uniformly distributed over 60–90%. Probabilities are calculated assuming no previous interim analysis. The total numbers of patients recruited at each month, of a total target of 1092, are 113 at 5 months, 153 at 6, 205 at 7, 257 at 8, 309 at 9, 361 at 10, 413 at 11, 465 at 12, 517 at 13, 569 at 14, 621 at 15, 673 at 16, 725 at 17, 777 at 18, 829 at 19, 881 at 20, 933 at 21, 985 at 22, 1037 at 23 and 1092 at 24. See Supplementary Figure 1, Additional file 1 for the cumulative probability of stopping a group.

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