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Table 3 Intra-cluster correlation coefficients for intermediate clinical outcomes

From: Intra-cluster correlation coefficients in primary care patients with type 2 diabetes and hypertension

Intermediate clinical outcomes

Number, N

Average cluster size

Mean (SD) or n (%)

ICC

95% CI

T2D PATIENTS WITH OR WITHOUT HYPERTENSION (N = 6722)

 HbA1c, %

6208

155

8.3 (2.2)

0.02

0.01, 0.03

 HbA1c ≤ 7%

6208

155

2135 (34.4)

0.01

0.002, 0.02

 HbA1c ≤ 8%

6208

155

3291 (53.0)

0.01

0.002, 0.02

 Systolic BP, mmHga

6712

168

137.8 (17.1)

0.08

0.06, 0.13

 Diastolic BP, mmHga

6712

168

77.8 (9.8)

0.08

0.05, 0.12

 BP ≤ 130/80 mmHg

6712

168

1936 (28.8)

0.09

0.05, 0.13

 BP ≤ 135/75 mmHg

6712

168

1757 (26.2)

0.06

0.03, 0.09

 BP ≤ 140/80 mmHg

6712

168

2991 (44.6)

0.08

0.05, 0.12

 Serum creatinine (μmol/L)

6455

162

88.6 (69.7)

0.01

0.01, 0.02

 TC (mmol/L)

6360

159

5.1 (1.2)

0.03

0.02, 0.06

 LDL-C (mmol/L)

5624

141

3.0 (1.1)

0.03

0.02, 0.05

 LDL-C ≤ 2.6 mmol/L

5624

141

2191 (39.0)

0.02

0.01, 0.03

 HDL-C (mmol/L)

5492

141

1.3 (0.4)

0.03

0.02, 0.05

 Triglycerides (mmol/L)

6335

159

1.8 (1.2)

0.01

0.01, 0.03

PATIENTS WITH HYPERTENSION (N = 5014)

 Systolic BP, mmHga

5004

126

137.8 (17.0)

0.08

0.05, 0.13

 Diastolic BP, mmHga

5004

126

78.7 (10.9)

0.09

0.06, 0.14

 BP < 140/90 mmHg [15]

5004

126

2644 (52.8)

0.05

0.02, 0.07

 Serum creatinine (μmol/L)

4738

119

83.2 (64.6)

0.01

0.01, 0.03

 TC (mmol/L)

4679

117

5.3 (1.1)

0.03

0.02, 0.06

 LDL-C (mmol/L)

3800

95

3.2 (1.0)

0.05

0.03, 0.09

 LDL-C ≤ 2.6 mmol/L

3800

95

1082 (28.5)

0.03

0.01, 0.05

 HDL-C (mmol/L)

3653

94

1.4 (0.4)

0.03

0.01, 0.05

 Triglycerides (mmol/L)

4685

118

1.5 (0.9)

0.01

0.004, 0.02

  1. BP blood pressure, CI confidence interval, HbA1c glycated haemoglobin, HDL-C high-density lipoprotein cholesterol, ICC intra-cluster correlation coefficient, LDL-C low-density lipoprotein cholesterol, SD standard deviation, T2D type 2 diabetes, TC total cholesterol
  2. aSystolic BP and diastolic BP values are the average of two readings