Intra-cluster correlation coefficients in primary care patients with type 2 diabetes and hypertension

Lee, Yi Lin; Lim, Yvonne Mei Fong; Law, Kian Boon; Sivasampu, Sheamini

doi:10.1186/s13063-020-04349-4

Trials

Table 2 Intra-cluster correlation coefficients for processes of care

From: Intra-cluster correlation coefficients in primary care patients with type 2 diabetes and hypertension

Processes of care	Number, N	Average cluster size	n (%)	ICC	95% CI
T2D PATIENTS WITH OR WITHOUT HYPERTENSION (N = 6722)
Test/assessment done within a specific interval
Test/assessment done on visit day
FBG	6722	168	3053 (45.4)	0.18	0.11, 0.25
RBG	6722	168	2685 (39.9)	0.14	0.08, 0.19
Blood pressure measurement	6707	168	6574 (97.8)	0.03	0.01, 0.05
At least 1 test/assessment within 3 months
HbA1c	6722	168	2450 (36.4)	0.09	0.05, 0.13
FBG	6722	168	3797 (56.5)	0.16	0.09, 0.22
Foot examination (pulse, neuropathy, ulcer)	6722	168	1837 (27.3)	0.17	0.10, 0.23
At least 1 test/assessment within 6 months
Body mass index	6696	167	2699 (40.2)	0.48	0.37, 0.59
At least 1 test/assessment within 12 months
Lipid profile
TC	6722	168	5376 (80.0)	0.03	0.01, 0.04
LDL-C	6722	168	4624 (68.8)	0.16	0.10, 0.22
HDL-C	6722	168	4614 (68.6)	0.16	0.10, 0.23
Triglycerides	6722	168	5300 (78.8)	0.02	0.01, 0.04
Complete lipid profile (TC, LDL-C, HDL-C, triglycerides)	6722	168	4533 (67.4)	0.16	0.10, 0.22
Serum creatinine	6722	168	5508 (81.9)	0.03	0.01, 0.04
Urine albumin	6722	168	3897 (58.0)	0.20	0.13, 0.28
Liver function	6722	168	3644 (54.2)	0.37	0.26, 0.47
Visual acuity examination	6722	168	3336 (49.6)	0.21	0.13, 0.28
Fundus examination	6722	168	2344 (34.9)	0.13	0.08, 0.18
Electrocardiography	6722	168	3248 (48.3)	0.22	0.14, 0.29
Medication prescribed
Glucose-lowering drugs
Biguanide (Metformin)	6722	168	5686 (84.6)	0.01	0.01, 0.02
Sulphonylurea	6722	168	3456 (51.4)	0.02	0.01, 0.03
Insulin	6722	168	1977 (29.4)	0.02	0.01, 0.03
Alpha-glucosidase inhibitor (acarbose)	6722	168	102 (1.5)	0.03	0.02, 0.05
Antihypertensive drugs
ACEI/ARB	6722	168	4242 (63.1)	0.04	0.02, 0.05
Calcium channel blocker	6722	168	4056 (60.3)	0.02	0.01, 0.03
Beta-blocker	6722	168	1717 (25.5)	0.03	0.01, 0.04
Diuretic	6722	168	1535 (22.8)	0.03	0.01, 0.05
Alpha-blocker	6722	168	380 (5.7)	0.02	0.01, 0.03
Lipid-lowering drugs
HMG-CoA reductase inhibitor (statin)	6722	168	5250 (78.1)	0.04	0.02, 0.06
Fibrate	6722	168	164 (2.4)	0.03	0.01, 0.04
PATIENTS WITH HYPERTENSION (N = 5014)
Test/assessment done within a specific interval
Test/assessment done on visit day
Blood pressure measurement	4985	125	4916 (98.6)	0.05	0.03, 0.08
At least 1 test/assessment done within 12 months
Blood glucose tests (FBG/RBG/HbA1c)	5014	126	3590 (71.6)	0.09	0.05, 0.13
Serum creatinine	5014	126	4005 (79.9)	0.06	0.03, 0.09
Urine albumin	5014	126	2087 (41.6)	0.23	0.15, 0.32
Lipid profile
TC	5014	126	3919 (78.2)	0.05	0.03, 0.08
LDL-C	5014	126	2954 (58.9)	0.22	0.14, 0.30
HDL-C	5014	126	2969 (59.2)	0.21	0.13, 0.29
Triglycerides	5014	126	3894 (77.7)	0.05	0.03, 0.08
Complete lipid profile (TC, LDL-C, HDL-C, triglycerides)	5014	126	2920 (58.2)	0.21	0.13, 0.29
Electrocardiography	5014	126	1802 (35.9)	0.28	0.18, 0.37
Medication prescribed
Antihypertensive drugs
Calcium channel blocker	5014	126	3972 (79.2)	0.01	0.002, 0.02
ACEI/ARB	5014	126	2210 (44.1)	0.04	0.02, 0.06
Beta-blocker	5014	126	1382 (27.6)	0.02	0.01, 0.04
Diuretic	5014	126	1054 (21.0)	0.02	0.01, 0.03
Alpha-blocker	5014	126	202 (4.0)	0.02	0.01, 0.03
Lipid-lowering drugs
HMG-CoA reductase inhibitor	5014	126	3427 (68.3)	0.04	0.02, 0.06
Fibrate	5014	126	63 (1.3)	0.01	0, 0.01

ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker, CI confidence interval, FBG fasting blood glucose, HbA1c glycated haemoglobin, HDL-C high-density lipoprotein cholesterol, HMG-CoA hydroxymethylglutaryl-coenzyme A, ICC intra-cluster correlation coefficient, LDL-C low-density lipoprotein cholesterol, RBG random blood glucose, T2D type 2 diabetes, TC total cholesterol

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