Skip to main content
Fig. 1 | Trials

Fig. 1

From: Is natural (6S)-5-methyltetrahydrofolic acid as effective as synthetic folic acid in increasing serum and red blood cell folate concentrations during pregnancy? A proof-of-concept pilot study

Fig. 1

Intestinal absorption of natural folate and folic acid. Legend: (1) food folates are hydrolyzed during digestion to the monoglutamate form; (2) Folic acid must be reduced to tetrahydrofolate in a two-step reaction by DHFR; (3) supplements in the natural form of folate, (6S)-5-methyltetrahydrofolic acid, may enter circulation directly for use in the body as 5-MTHF; and (4) both food folates and folic acid are ultimately metabolized to 5-MTHF by MTHFR

Back to article page