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Table 3 Protocol glucocorticoid dose-tapering regimens for patients given prednisone during the first 10 weeks (of each study stage) for a skin vasculitis flare

From: Protocol for a randomized multicenter study for isolated skin vasculitis (ARAMIS) comparing the efficacy of three drugs: azathioprine, colchicine, and dapsone

Time from initiation

Daily dose Option 1

Daily dose Option 2

Days 1–3

30 mg/day

10 mg/day

Days 4–6

20 mg/day

7.5 mg/day

Days 7–9

15 mg/day

5 mg/day

Days 10–12

10 mg/day

2.5 mg/day

Days 13–15

5 mg/day

0

Days 16–18

2.5 mg/day

0

Day 19

0

0

  1. At week 12 (Stages 1 and 2), all patients must be off prednisone
  2. For patients requiring a second course of prednisone for vasculitis flare, the study drug will be considered a treatment failure