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Table 3 Probability of one treatment being better

From: International randomised controlled trial for the treatment of newly diagnosed EWING sarcoma family of tumours – EURO EWING 2012 Protocol

Observed 3-year EFS

Observed HR

P (HR <1.00)

P (HR <0.81)

P (HR >1.21)

VIDE

Difference

VDC/IE

Number of events

HR

ln (HR)

0.70

0.00

0.70

180

1.00

0.00

0.50

0.07

0.10

0.70

0.05

0.75

165

0.81

−0.21

0.92

0.50

0.00

0.70

−0.05

0.65

195

1.21

0.19

0.09

0.00

0.50

0.70

0.025

0.725

173

0.90

−0.10

0.75

0.23

0.03

0.70

− 0.025

0.675

188

1.10

0.10

0.25

0.02

0.27

  1. EFS event-free survival, HR hazard ratio, VDC/IE vincristine, doxorubicin, cyclophosphamide, ifosfamide and etoposide, VIDE vincristine, ifosfamide, doxorubicin and etoposide