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Fig. 1 | Trials

Fig. 1

From: Bayesian group sequential designs for phase III emergency medicine trials: a case study using the PARAMEDIC2 trial

Fig. 1

Key operating characteristics for Bayesian designs across several treatment effects and survival rates. The mean sample size is shown in the left column and the probability of declaring a difference between the trial arms is shown in the right column. The treatment effect is the raw difference between adrenaline and placebo survival rates. A positive treatment effect corresponds to adrenaline being superior; a negative treatment effect corresponds to adrenaline being harmful. The horizontal line in the right column figures represents a type I error of 5%

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