INtervention for Cognitive Reserve Enhancement in delaying the onset of Alzheimer’s Symptomatic Expression (INCREASE), a randomized controlled trial: rationale, study design, and protocol

Table 3 Study outcomes

Study outcomes
Primary	Medication appropriateness	MAI	Change from pre- to post-intervention
Primary	Executive function	TMTB	CRCS: difference in scopolamine-challenged and unchallenged z-scores
Secondary	Global cognition	MoCA
	Memory	CVLT
	Perceived health status	SF-36	Change from pre- to post-intervention

MAI medication appropriateness index, TMTB Trail Making Test B, CVLT California Verbal Learning Test, MoCA Montreal Cognitive Assessment, SF-36 Short-Form 36

ISSN: 1745-6215