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Table 5 Baseline characteristics of participants with and without at least 1 Social adverse event (AE)

From: Monitoring adverse social and medical events in public health trials: assessing predictors and interpretation against a proposed model of adverse event reporting

 At least 1 Social AE
N = 208
Participants without a Social AE
N = 1410
Unadjusted ORa (95% CI), p valueAdjusted ORb (95% CI), p value
nMedian (25th to 75th centile) or %nMedian (25th to 75th centile) or %  
Baseline characteristic
 Maternal age (years)20817.6 (16.7 to 18.6)141017.9 (17.0 to 18.8)0.84 (0.74 to 0.94), 0.0040.78 (0.67 to 0.90), 0.001
 Ethnicity    Overall p value = 0.189 
  White background19091.3123587.6Ref 
  Mixed background136.2765.41.07 (0.57 to 2.02), 0.834 
  Asian background31.4241.70.59 (0.15 to 2.26), 0.439 
  Black background21.0694.90.22 (0.05 to 0.95), 0.042 
  Other background00.060.4 
 Relationship status    Overall p value = 0.275 
  Married21.0181.3Ref 
  Separated2713.01389.82.13 (0.44 to 10.30), 0.346 
  Closely involved/boyfriend15675.0106675.61.46 (0.32 to 6.78), 0.627 
  Just friends2311.018813.31.20 (0.24 to 5.87), 0.823 
 Live with father of baby
  No12768.398576.1Ref 
  Yes5931.730923.81.32 (0.94 to 1.88), 0.113 
  Missing22 116   
 Family subjective social status2075.4 (5.0 to 7.0)14005.6 (5.0 to 7.0)0.90 (0.83 to 0.99), 0.0221.01 (0.91 to 1.12), 0.879
 Personal subjective social status2086.7 (5.0 to 8.0)14036.9 (6.0 to 8.0)0.92 (0.85 to 1.00), 0.0410.96 (0.88 to 1.05), 0.386
 NEETc:
  No8953.972059.3Ref 
  Yes7646.149540.71.41 (1.00 to 1.98), 0.050 
  Not applicable43 195   
 Receive any benefits
  No11253.892065.3RefRef
  Yes9646.248834.71.61 (1.19 to 2.18), 0.0021.60 (1.09 to 2.35), 0.016
  Missing0 2   
 Ever been homeless
  No14167.8116382.5RefRef
  Yes6732.224717.52.08 (1.49 to 2.91), < 0.0011.50 (0.99 to 2.28), 0.059
 Socio-economic status: Index of Multiple Deprivation Scored20739.1 (24.5 to 51.6)139939.2 (25.2 to 52.1)1.01 (1.00 to 1.02), 0.188 
 EQ5D-Binary
  Less than perfect health9746.648834.7RefRef
  Perfect health11153.491965.30.70 (0.51 to 0.95), 0.0230.94 (0.63 to 1.38), 0.739
  Not answered0 3   
 Self-rated health    Overall p value = 0.414 
  Excellent2813.523516.7Ref 
  Good14368.894266.81.23 (0.79 to 1.91), 0.355 
  Fair3215.422015.61.17 (0.67 to 2.04), 0.573 
  Poor52.4130.92.61 (0.82 to 8.27), 0.103 
 Limiting long-term illness:
  No16076.9117983.6RefRef
  Yes4823.123116.41.38 (0.96 to 2.00), 0.0861.17 (0.77 to 1.77), 0.460
 Generalized Self-efficacy Scalee20429.2 (27.0 to 32.0)138830.1 (28.0 to 33.0)0.95 (0.92 to 0.98), 0.002 
 Adaptive functioningf
 Difficulty in at least 1 basic skill
  No13765.9104874.5refRef
  Yes7134.135925.51.70 (1.23 to 2.35), 0.0011.36 (0.94 to 1.96), 0.103
  Missing0 3   
 Adaptive functioningf
 Had 3 or less life skills (out of 5)
  No15775.8102172.7Ref 
  Yes5024.238427.30.92 (0.65 to 1.31), 0.648 
  Missing1 5   
 Adaptive functioningf
 At least 1 burden
  No13465.099771.2Ref 
  Yes7235.040428.81.25 (0.91 to 1.72), 0.172 
  Missing1 9   
 Substance abuseg1991.6 (0.0 to 3.0)13991.3 (0.0 to 2.0)1.23 (1.02 to 1.24), 0.0140.93 (0.83 to 1.05), 0.233
 Antisocial behaviour Score2053.1 (2.0 to 4.0)14042.3 (1.0 to 4.0)1.30 (1.19 to 1.42), < 0.0011.22 (1.09 to 1.36), < 0.001
 Social support20581.5 (73.7 to 96.1)139885.4 (77.6 to 98.7)0.99 (0.98 to 0.996), 0.0031.00 (0.99 to 1.01), 0.969
 Relationship quality17126.9 (24.0 to 31.0)110628.2 (26.0 to 32.0)0.94 (0.91 to 0.97), < 0.001Not includedh
 Family resources20312.4 (9.5 to 15.0)134813.5 (11.0 to 17.0)0.93 (0.90 to 0.97), < 0.0010.96 (0.92 to 1.00), 0.063
 Psychological distress/mental health20723.0 (18.0 to 27.0)140221.3 (16.0 to 26.0)1.03 (1.01 to 1.06), 0.0031.01 (0.98 to 1.04), 0.585
 Arm
  Control10048.171050.4Ref 
  Intervention10851.970049.61.10 (0.81 to 1.48), 0.545 
  1. aOR predicts a Social AE and adjusted for site; bAdjusted for site and all other candidate predictors in model; cDefinition of Not in Education, Employment, or Training (NEET): not in education employment or training status (applicable only to those whose academic age is > 16 years at baseline interview); dHigher IMD score indicated more deprivation; eHigher score indicates higher level of self-efficacy; fHigher score indicates better management of day-to-day lives and routines (for each of the three sub-scales); gCRAFFT screening test for substance related risks and problems in adolescents; h due to question only applicable to those in a relationship
  2. Odds ratios (ORs) bolded and in italics indicate variable significant at 10% at univariable level and remained so at multivariable level