Claims | |
• Treatments may be harmful. • Personal experiences or anecdotes (stories) are an unreliable basis for assessing the effects of most treatments. • Widely used treatments or treatments that have been used for a long time are not necessarily beneficial or safe. • New, brand-named, or more expensive treatments may not be better than available alternatives. • Opinions of experts or authorities do not alone provide a reliable basis for deciding on the benefits and harms of treatments. • Conflicting interests may result in misleading claims about the effects of treatments. | |
Comparisons | |
• Evaluating the effects of treatments requires appropriate comparisons • Apart from the treatments being compared, the comparison groups need to be similar (i.e., ‘like needs to be compared with like’). • If possible, people should not know which of the treatments being compared they are receiving. • Small studies in which few outcome events occur are usually not informative, and the results may be misleading. • The results of single comparisons of treatments can be misleading. | |
Choices | |
• Treatments usually have beneficial and harmful effects. |