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Table 3 Magnetic resonance imaging sequences and parameters

From: KARAOKE: Krill oil versus placebo in the treatment of knee osteoarthritis: protocol for a randomised controlled trial

Study site

Machine and coils

T2 weighted sagittal 3D

T1-weighted sagittal 3D

T2 mapping

Hobart

1.5 T whole-body MR unit (GE Optima 450 W, Milwaukee, USA), using a dedicated Transmit/Receive 8-channel knee coil where patient size permits, if body habitus is too large we use a 16 channel large GEM Flex coil

T2 weighted fat-saturated 3D fast spin echo sequence; repetition time 2300 ms; echo time 80 ms; field of view 18 cm; 256 × 256 matrix with interpolation Recon Voxel 0.35 × 0.35 × 1 mm; 2 excitation; slice thickness 1 mm

T1-weighted fat-saturated 3D gradient-recalled acquisition; flip angle 30 degrees; repetition time 38 ms; echo time 3 ms; field of view 16 cm; 256 × 160 matrix Reconstructed Voxel 0.625 × 1 × 1.5 mm; 1 excitation; slice thickness 1.5 mm

T2 mapping; repetition time 1100 ms; echo time 6.6 ms; field of view 16 cm; 320 × 224 matrix Reconstructed Voxel 0.5 × 0.714 × 3 mm; 1 excitation; slice thickness 3 mm

Perth

1.5 T whole-body MR unit (Siemens, Magnetom Avanto Fit, Erlangen, Germany), using a dedicated Transmit/Receive 15 channel knee coil

T2 weighted fat-saturated 3D fast spin echo sequence; flip angle mode T2; repetition time 1400 ms; echo time 89 ms; field of view 19 cm; 256 × 256 matrix with interpolation Recon Voxel 0.4 × 0.4 × 1.5 mm; 1 excitation; slice thickness 1.5 mm

T1-weighted fat-saturated 3D gradient-recalled acquisition; flip angle 10 degrees; repetition time 13.9 ms; echo time 6.05 ms; field of view 19 cm; 320 × 298 matrix Reconstructed Voxel 0.6 × 0.6 × 1.5 mm; 1 excitation; slice thickness 1.5 mm

T2 mapping (multi echo SE); flip angle 180 degrees; repetition time 1890 ms; echo time 13.8, 27.6, 41.4, 55.2, 69.0 ms; field of view 16 cm; 256 × 256 matrix Reconstructed Voxel 0.63 × 0.63 × 3 mm; 1 excitation; slice thickness 3 mm

Adelaide

3 T whole-body MR unit (Siemens Magnetom Skyra 3Tesla), using a dedicated 15 channel knee coil

T2 weighted fat-saturated 3D SPACE; repetition time 2200 msec; echo time 121 msec; field of view 16 cm; 320 × 320 matrix; 1 excitation; slice thickness 0.6 mm

T1-weighted Water Excitation 3D gradient-recalled acquisition VIBE; flip angle 16 degrees; repetition time 10.4 ms; echo time 5.7 ms; field of view 160 cm; 320 × 298 matrix; 1 excitation; slice thickness 1 mm

T2 mapping (multi echo acquisition); flip angle 180 degrees; repetition time 1750 ms; echo time 13.8/27.6/41.4/55.2/69 ms; field of view 16 cm; 320 × 320 matrix; 1 excitation; slice thickness 3 mm

Melbourne

3 T whole-body MR unit (Siemens, (Skyra 3 T) Magnetom Avanto Fit, Erlangen, Germany), using a dedicated Transmit/Receive 15 channel knee coil

T2 weighted fat-saturated 3D fast spin echo sequence; flip angle mode T2; repetition time 1200 ms; echo time 50 ms; field of view 16 cm; 230 × 320 matrix without interpolation not on; Recon Voxel 0.5 × 0.5 × 0.6 mm; 1 excitation; slice thickness 0.6 mm

T1-weighted fat-saturated 3D gradient-recalled acquisition; flip angle 30 degrees; repetition time 11.7 ms; echo time 5.61 ms; field of view 16 cm; 320 × 320 matrix Reconstructed Voxel 0.5 × 0.5 × 1.5 mm; 1 excitation; slice thickness 1.5 mm

T2 mapping (multi echo SE); flip angle 180 degrees; repetition time 1840 ms; echo time 11.7, 23.4, 35.1, 46.8, 58.5 ms; field of view 16 cm; 307 × 384 matrix Reconstructed Voxel 0.4 × 0.4 × 3 mm; 1 excitation; slice thickness 3 mm

Sydney

3 T whole-body MR unit (Siemens, Magnetom Skyra, Erlangen, Germany), using a dedicated Transmit/Receive 15 channel knee coil

T2 weighted fat-saturated 3D fast spin echo sequence; flip angle mode T2; repetition time 1000 ms; echo time 108 ms; field of view 16 cm; 256 × 256 matrix without interpolation Recon Voxel 0.6 × 0.6 × 0.6 mm; 1 excitation; slice thickness 0.6 mm

T1-weighted fat-saturated 3D gradient-recalled acquisition; flip angle 25 degrees; repetition time 11.6 ms; echo time 4.7 ms; field of view 16 cm; 256 × 256 matrix Reconstructed Voxel 0.6 × 0.6 × 1 mm; 1 excitation; slice thickness 1 mm

T2 mapping (multi echo SE); flip angle 180 degrees; repetition time 2150 ms; echo time 13.8, 27.6, 41.4, 55.2, 69.0 ms; field of view 16 cm; 384 × 326 matrix Reconstructed Voxel 0.42 × 0.42 × 3 mm; 1 excitation; slice thickness 3 mm