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Table 1 Summary of primary, secondary and tertiary outcome measures, potential mediating and risk factors, and data collection time points

From: A trial protocol for the effectiveness of digital interventions for preventing depression in adolescents: The Future Proofing Study

Outcome measure

Baseline

Post (Stage I)

6 months

12months

Post (Stage II)a

24 months

36 months

48 months

60 months

Primary outcome measure

 Depression

Patient Health Questionnaire: Adolescent Version (PHQ-A)

✓

✓

✓

✓

✓

✓

✓

✓

✓

Secondary outcome measures

 Psychological distress

Distress Questionnaire 5 (DQ5)

✓

✓

–

✓

–

✓

✓

✓

✓

 Anxiety

Spence Children’s Anxiety Scale (SCAS) including Generalized Anxiety and Social Phobia subscales

✓

✓

–

✓

✓

✓

✓

✓

✓

 Insomnia

Insomnia Severity Index (ISI)

✓

✓

–

✓

✓

✓

✓

✓

✓

Tertiary outcome measures, potential mediating variable risk factors

 Suicidal ideation

Suicidal Ideation Attributes Scale (SIDAS)

✓

✓

–

✓

–

✓

✓

✓

✓

 Suicide behaviour

Youth Risk Behaviour Survey (YRBS)

✓

✓

–

✓

–

✓

✓

✓

✓

 Externalising behaviours

Strength and Difficulties Questionnaire (SDQ)

✓

✓

–

✓

–

✓

✓

✓

✓

 Eating disorders

Screen for Disordered Eating (SDE)

✓

✓

–

✓

–

✓

✓

✓

✓

 Self-harm

Single question from Self-Harm Questionnaire

✓

✓

–

✓

–

✓

✓

✓

✓

 Alcohol use

Questions from previous National Drug and Alcohol Research Centre, UNSW studies

✓

✓

–

✓

–

✓

✓

✓

✓

 Other substance use

Questions from Australian Institute of Health and Welfare 2007 National Drug Strategy Household Survey

✓

✓

–

✓

–

✓

✓

✓

✓

 Psychosis

Adolescent Psychotic-like Symptom Screener (APSS)

✓

✓

–

✓

–

✓

✓

✓

✓

 Sleep quality

Pittsburgh Sleep Quality Index (PSQI)

✓

✓

–

✓

✓

✓

✓

✓

✓

 Quality of life

Child Health Utility 9D (CHU-9D)

✓

✓

–

✓

–

✓

✓

✓

✓

 Well-being

Short-form Warwick–Edinburgh Mental Well-Being Scale (SWEMWBS)

✓

✓

–

✓

–

✓

✓

✓

✓

 Demographics

Age, ethnicity, location, language, perceived socio-economic status

✓

–

–

–

–

–

–

–

–

 Height and weight

Height (cm), weight (kg)

✓

–

–

✓

–

✓

✓

✓

✓

 Personality

Big Five Inventory-10 (BFI-10)

✓

–

–

–

–

–

–

–

–

 School connectedness

Items from OECD Programme for International Student Assessment (PISA)

✓

✓

–

✓

–

✓

✓

✓

–

 Social support

Schuster Social Support Scale (SSSS)

✓

✓

–

✓

–

✓

✓

✓

✓

 Social media use

Maladaptive Facebook Use Survey (MFUS), adapted to apply to social media use more broadly

✓

✓

–

✓

–

✓

✓

✓

✓

 Gender identification

Sex at birth and current gender identification

✓

–

–

✓

–

✓

✓

✓

✓

 Sexual identification and preferences

Single item for each

✓

–

–

✓

–

✓

✓

✓

✓

 Sexual behaviour

History of sexual behaviour

–

–

–

–

–

✓

 

✓

 

 Romantic relationships

History of romantic relationships

✓

  

✓

 

✓

✓

✓

✓

 Trauma

Adapted Behavioural Risk Factor Surveillance System—Adverse Childhood Experience (BRFSS-ACE)

✓ no abuse items

–

–

–

–

–

–

✓

–

 History of diagnosed mental health condition

Diagnosed mental health conditions

✓

✓

–

✓

–

–

–

✓

✓

 Hospitalisation

History of hospitalisation

✓

✓

–

✓

–

–

–

✓

✓

 History of diagnosed disability

Diagnosed disability

✓

–

–

–

–

–

–

✓

–

 Pubertal development

Menarche, voice-breaking and Tanner stages

✓

–

–

✓

–

✓

✓

✓

✓

 Bullying

From previous school trials

✓

✓

–

✓

–

✓

✓

✓

✓

App feedback/acceptability

 App feedback

Future Proofing App Feedback Survey

–

✓

–

–

–

–

–

–

–

 App feedback

Post-intervention SPARX-FP Feedback Survey

–

✓

–

–

–

–

–

–

–

  1. UNSW University of New South Wales
  2. aParticipants selected to take part in Stage II of the trial only