Fig. 3From: Testing non-inferiority of blended versus face-to-face cognitive behavioural therapy for severe fatigue in patients with multiple sclerosis and the effectiveness of blended booster sessions aimed at improving long-term outcome following both therapies: study protocol for two observer-blinded randomized clinical trialsIllustration of a possible result of the non-inferiority tria. Difference between face-to-face CBT and blended CBT and the 95% CI. H0: blended CBT is inferior to face-to-face CBT, meaning that face-to-face CBT – blended CBT ≥ M. Mis the non-inferiority margin (6.67–5.32 = 1.35). H1: blended CBT is non-inferior to face-to-face CBT, meaning that face-to-face CBT – blended CBT < MlBack to article page