Fig. 1From: Efficacy and safety of dexmedetomidine for prevention of withdrawal syndrome in the pediatric intensive care unit: protocol for an adaptive, multicenter, randomized, double-blind, placebo-controlled, non-profit clinical trialStandard Protocol Items: Recommendations for Interventional Trials (SPIRIT) figure: schedule of enrolment, interventions and assessments of the trial. AE adverse event, AR adverse reactions, AS analgosedation, PICU pediatric intensive care unit, SUSAR serious adverse events and suspected unexpected serious adverse reaction, treatment A receiving dexmedetomidine, treatment B receiving placebo, WAT-1 Withdrawal Assessment Tool version 1Back to article page