Table 1 Schedule of enrolment, interventions and assessments for the clinical trial

 Medical history and physical examination

X

 Explanation of the study and informed consent

X

 Initial CRF

X

 Giving out of the symptom diary, up to week 2

X

 CRP rapid test if needed (only among those patients visited by professionals assigned to the CRP intervention groups)*

X

 Use of an interactive booklet (only among those patients visited by professionals assigned to the enhanced communication skill intervention groups)*

X

 Assessment of the clinical outcome

X

X

 Collection and review of the symptom diary

X

 EQ-5D-5L questionnaire

X

X

X

 Antibiotic consumption

X

X

X

 Use of drugs other than antibiotics

X

X

X

 Tests ordered by clinicians

X

X

X

 Patient satisfaction with care

X

X

 Patient perception of the usefulness of the information received

X

X

 Patient future consulting intentions

X

X

 Absenteeism

X

X

X

 Evaluation of adverse events

X

X

 Number of re-consultations to primary and secondary care and number of complications regarding the ALRTI

X