Name | Scoring/description | Test metrics |
---|---|---|
Primary outcome measures | ||
 Dizziness Handicap Inventory (DHI) | 25 items, each item has 3 alternative scores 0 (no), 2 (sometimes) and 4 (yes) giving a score range of 0–100 DHI points [37]. Higher scores indicate greater perceived disability; 0–30; mild, 31–60; moderate, 61–100; severe [38] | Cut-off 29 points, MIC 11 DHI points, ICC 1,1 0.90 [39]. |
 Preferred gait velocity (m/s) | Participants walked at normal pace, down an 8-m pathway, timed in the middle 6 m. It was timed using a stopwatch from when the first foot passed the start point to when the last foot passed the stop point. Mean velocity over two trials were calculated | Substantial meaningful change 0.1 m/s [40], ICC (3.1): 0.88 (CI 0.81–0.98) [41] |
Secondary outcomes/patient-reported outcomes | ||
 The shortened version of the Vertigo Symptom Scale (VSS) | 15 items, each scoring from 0 (never) to 4 (very often) giving a score range of 0–60. Higher scores indicate greater symptom severity [42]. Severe dizziness ≥ 12 [42] | Norwegian version cut-off, 6.5 points [43]. Clinically significant change in original version ≥ 3 points [44]. ICC Norwegian version, 0.89 [43] |
 Agoraphobic Cognitions Questionnaire (ACQ) | 14 items, each rated on a scale ranging from 1 (thought never occurs when I am nervous) to 5 (thought always occurs when I am nervous) [45]. Measures fear of fear. The mean score is reported, and higher scores imply greater levels of fear | Cronbach’s alpha for outpatients with agoraphobia, 0.80 [45] |
 Body Sensation Questionnaire (BSC) | 18 items, each with a score range from 1 (not at all frightened by the sensations) to 5 (extremely frightened by this sensation). The mean score reported, and higher scores implies greater fear of somatic sensations [45] | Cronbach’s alpha for outpatients with agoraphobia, 0.87 [45] |
 Mobility Inventory of Agoraphobia-Alone (MIA) | 27 items, each rated from 1 (never avoids) to 5 (always avoids). The mean score is reported and, and higher scores indicate greater avoidance behaviour | Cronbach’s alpha in agoraphobia, 0.96 [46] |
Adapted Panic Attack Scale | ||
• Attack frequency | Measures frequency of distress related to sudden onsets of episodes with 4 or more strong sensations of dizziness and dizziness related symptoms on a 5-point scale ranging from 0 (no attacks) to 4 (one or more attacks per day). Adapted from the Panic Attack Scale [47] |  |
• Attack severity | Severity rating of the degree of distress related to the episodes described above. Numeric rating scale with a score range 0–8. Higher scores indicates increased symptom-related distress/disability. Adapted from the Panic Attack Scale [47] |  |
Hospital Anxiety and Depression Scale (HADS) | 14 items, each rated from 0 (not present) to 3 (considerable), giving a score range of 0–42 points [48]. Higher scores indicates greater psychological distress | Cut-off 12 points, Cronbach’s alpha, 0.88. [49] |
EQ-5D-5 L | Generic instrument describing and valuing health [50]. |  |
• EQ-5D-5 L | Five dimensions, each rated from 1 to 5. Higher scores indicate increased health problems [51] |  |
• EQ-5D-5 L Vas | Score range 0–100%. Higher scores indicate better perceived health-related quality of life | MCID in stroke,:8.61–10.82 [52] |
Subjective Health Complaints (SHC) | 29 items, each item is scored from 0 (no complaints) to 3 (serious complaints). Higher scores indicate greater severity of complaint. Split into 5 subcategories: Musculoskeletal 8 items (score 0–24), Pseudoneurology 7 items (score 0–21), Gastrointestinal 7 items (score 0–21), Flu 2 items (score 0–6) and Allergy 5 items (score 0–15) [53] | Cronbach’s alpha musculoskeletal pain, 0.74; Pseudoneurology, 0.73; Gastrointestinal, 0.62; Allergy, 0.58; and Flu, 0.67 [53] |
Chalder’s Fatigue Questionnaire (CFQ) | 13 items. The first 11 items are scored from 0 (better than usual) to 3 (much worse than usual), giving a score range of 0–33. The last 2 items rate duration and constancy of fatigue [54]. Higher scores indicating more fatigued | Cronbach’s alpha in Norwegian population, 0.86 [55] |
Patient Specific Functional Scale (PSFS) | Registers up to 3 activities that participants find difficult. In addition, the level of difficulty is rated on an 11-point scale [56], where 0 maximum difficulty and 10 is no difficulty | Reliability established in various musculoskeletal problems (ICC 0.76–0.97) [57] MCID in various musculoskeletal problems, 0.99–2.5 [57] |
Patient Global Impression of Change (PCIG) | 1item, rated from 1 (very much improved) to 7 (very much worse), with a score of 4 indicating no change [58] | Â |
Secondary outcomes/physical tests | ||
 Dual-task walking | Similar walking protocol as for preferred gait velocity, with an added task of counting backwards by 3 out loud, while walking. Each trial was timed and the numbers of miscounts were documented. Mean velocity, and mistakes over 2 trials calculated |  |
 Fast gait velocity (m/s) | Similar protocol to preferred gait velocity; however, participants were asked to walk as fast as possible |  |
 Clinical dynamic visual acuity (CDVA) | Evaluates gaze stability by assessing visual acuity using examiner-mediated head oscillations at 2 Hz relative to head being stationary | Cut-off ≥ 3 lines indicates potential vestibular hypofunction [59]. Reliability in bilateral peripheral hypofunction ICC (2.2): 0.94 [60] |
 Head-movement-induced dizziness | Perceived dizziness reported using the Numeric Rating Scale (NRS) on 2 conditions: 1 while sitting stationary, and 1 after 1 min of active head oscillations at 1 Hz (following a metronome). Score range 0 (no dizziness) to 10 (as bad as it can be), with higher scores indicating higher perceived intensity of head-movement-induced dizziness. Difference between the two conditions will also be calculated | VAS head-movement-induced dizziness [41], reliability 0.48 for all subjects, reliability 0.82 for male subjects |
 Grip strength | Maximal grip strength in both hands assessed using a hand-held dynamometer. Measured in kg. Averaged between 2 trials calculated for each hand | Genuine change in healthy adults, 6 kg [61] |
 Body sway while standing | Assessed using the modified test for interaction and balance (mCTSIB) with arms crossed over the chest, using the HURlabs balance trainer BTG4; 4 conditions tested: standing with eyes open and closed, on a firm surface or on a foam cushion. Each trial is timed for 30 s | ICC in healthy subjects, 0.91–0.97 [62] |
 Elements from the Global Physiotherapy Examination (GPE) | 4 elements from the main domain Movement of the GPE examination were selected [17, 36]. The items include lumbo-sacral flexion, head-nod flexion, shoulder retraction and elbow drop. Score range − 2.3 to 2.3, scored in relation to a predefined standard (0) [36] | ICC 2.1 lumbo-sacral flexion, 0.82; ICC 2.1 head-nod flexion, 0.84; ICC 2.1 shoulder retraction, 0.75; ICC 2.1 elbow drop, 0.89 (personal communication: A. Kvåle) |