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Table 2 Criteria for spontaneous breathing trial failure

From: Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial

A failed SBT will be defined by the presence of any ONE of:

(1) A respiratory rate > 35 breaths/min with signs of respiratory distress or an increase in respiratory rate ≥ 20% from baseline with signs of respiratory distress

(2) Oxygen saturation of arterial blood (SaO2) or pulse oximetry < 90%

(3) Heart rate > 140 beats/min with signs of respiratory distress or an increase in HR ≥ 20% from baseline with signs of respiratory distress

(4) Systolic blood pressure ≥ 180 or ≤ 90 mmHg

(5) The presence of somnolence, agitation, diaphoresis, or anxiety

(6) Requirement for the addition of or an increase in vasopressor or inotropic agent support

(7) Chest pain or other limiting pain precluding further continuation