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Table 2 Statistical powers provided by a sample size of n = 42 (21 per group) if two lesions are evaluable per subject

From: Comparative study of the inhibitory effect on bone erosion progression with denosumab treatment and conventional treatment in rheumatoid arthritis patients: study protocol for an open-label randomized controlled trial by HR-pQCT

Effect size (between-group difference)

1.0 mm

Standard deviation

1.1 mm

1.3 mm

Intra-subject correlation

0.1

0.3

0.5

0.1

0.3

0.5

Statistical power

97.1%

94.5%

91.5%

90.8%

85.8%

80.1%