Table 1 Composition and action of yinang formulation in Chinese herbal medicine

Rhizoma sparganii (sanleng)

10 g

1. Regulate qi

2. Relieve pain

3. Promote blood circulation

4. Alleviate stagnation

1. Inhibit platelet aggregation and thrombosis

Ranunculus ternatus Thunb

(maozhuacao)

30 g

1. Dissipate phlegm

2. Dispel stasis

3. Detoxify

4. Detumescence

1. Anti-inflammation

2. Anti-tumor

Spina gleditsiae (zaojiaoci)

6 g

1. Detoxify

2. Disperse swelling

1. Anti-tumor

Rhizoma drynariae (gusuibu)

10 g

1. Reinforce the kidneys

2. Strengthen bones

3. Relieve pain

1. Prevent osteoporosis

2. Anti-inflammatory

Astragalus (huangqi)

30 g

1. Tonify qi

2. Diuresis

1. Improve the immune function

2. Anti-oxidant

3. Increase resistance to radiation

4. Anti-tumor

Codonopsis pilosula (dangshen)

30 g

1. Invigorate the spleen

2. Replenish qi

1. Regulate the central nervous system

2. Enhance immune function

3. Regulate gastrointestinal motility

4. Cardiovascular protective effect

Angelica sinensis (danggui)

10 g

1. Enrich the blood

2. Invigorate the circulation of blood

1. Anti-atherosclerosis

2. Bacteriostasis

3. Anti-hypoxia

4. Regulation of immune function 5. Inhibit platelet aggregation

Paeoniae radix (chishao)

15 g

1. Activate blood circulation to dissipate blood stasis

1. Inhibition of platelet and erythrocyte aggregation

2. Anti-atherosclerosis

3. Anti-tumor

4. Protect the heart and liver

5. Anti-coagulation and anti-thrombosis

Radix paeoniae alba (baishao)

10 g

1. Nourish the blood

2. Reduce yin

3. Soothe the liver

4. Relieve pain

5. Stabilize yin and yang in the liver

1. Anti-inflammation

2. Pain relief

3. Liver protection

Duchesnea indica (shemei)

10 g

1. Clear away heat and toxic material

2. Activate blood circulation to dissipate blood stasis

1. Anti-oxidant

Hedyotis diffusa willd (baihuasheshecao)

15 g

1. Dissolve phlegm

2. Detoxification

3. Detumescence

1. Anti-inflammation

2. Anti-tumor

3. Regulation of immune function

Cowherb seed (wangbuliuxing)

15 g

1. Activate blood circulation to dredge collaterals

2. Detumescence

3. Relieve pain

1. Inhibit microcapillary proliferation

2. Inhibit migration and adhesion of endothelial cells

Semen brassicae (baijiezi)

15 g

1. Activate qi

2. Activate blood circulation

3. Dredge collaterals

4. Relieve pain

1. Anti-hepatic fibrosis

2. Regulation of TGF-β1/Smad, NF-κB, and AKT signaling pathways

3. Reduction of extracellular matrix deposition

Plantaginis seeds (cheqianzi)

15 g

1. Clear heat

2. Diuresis

3. Permeate dampness

4. Promote circulation

5. Clear eyesight

6. Expectorant

1. Eliminate oxygenic free radicals

2. Anti-oxidation in lipid metabolism

3. Anti-oxidation

Polygonum cuspidatum (huzhang)

10 g

1. Relieve coughing

2. Resolve phlegm

3. Dispel wind dampness

4. Remove fluid

5. Dissipate blood stasis

6. Relieve pain

1. Anti-bacterial and anti-viral

2. Protect the cardiovascular system

3. Anti-inflammation and analgesic

4. Liver protection

5. Enhance immunity

6. Anti-tumor

Centella asiatica (jixuecao)

30 g

1. Clear heat

2. Disperse dampness

3. Detoxify

4. Reduce swelling

1. Improve the microcirculation

2. Relieve pain

3. Anti-oxidant

4. Anti-bacterial

5. Anti-inflammation

6. Anti-fibrous tissue proliferation

Prepared rhubarb (dahuang)

10 g

1. Alleviate accumulation

2. Clear heat

3. Detoxify

4. Remove blood stasis

5. Dredge meridians

1. Promote defecation

2. Anti-bacterial

3. Protect the liver and gallbladder 4. Lower blood pressure

5. Lower blood lipid levels