Table 2 Primary and secondary outcomes
Outcomes | EA (n) | MA (n) | SAb (n) | P value | Pairwise comparison | |||||
|---|---|---|---|---|---|---|---|---|---|---|
EA vs. SA | MA vs. SA | EA vs. MA | ||||||||
Difference (95% CI) | P value | Difference (95% CI) | P value | Difference (95% CI) | P value | |||||
Success rate, no. (%) | ||||||||||
4 weeks | x (xx.x) | x (xx.x) | x (xx.x) | – | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | – | – |
8 weeks | x (xx.x) | x (xx.x) | x (xx.x) | – | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | – | – |
16 weeks | x (xx.x) | x (xx.x) | x (xx.x) | – | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | – | – |
26 weeks | x (xx.x) | x (xx.x) | x (xx.x) | – | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | – | – |
Numerical Rating Scale, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
WOMAC pain subscale, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
WOMAC function subscale, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
WOMAC stiffness subscale, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
Patient global assessment, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
SF-12 physical health, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
SF-12 mental health, mean (SD) | ||||||||||
Baseline | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x | xx.x (xx.x- xx.x) | xx.x |
4 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
8 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
16 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||
26 weeks | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | xx.x (xx.x- xx.x) | ||||