Table 3 Timing of outcomes to be assessed
Time point | |||||
|---|---|---|---|---|---|
Baseline | 3 months | 6 months | 9 months | 12 months | |
FENO | ✓ | ✓ | ✓ | ✓ | ✓ |
Smartinhaler® data | ✓ | ✓ | ✓ | ✓ | |
Respiratory case report form (current medication, recent asthma history and attacks, inhaler technique, etc.) | ✓ | ||||
Asthma Control Test | ✓ | ✓ | ✓ | ✓ | ✓ |
Paediatric Asthma Quality of Life Questionnaire | ✓ | ✓ | |||
Spirometry (FEV1) and height | ✓ | ✓ | ✓ | ✓ | ✓ |
Weight | ✓ | ✓ | |||
Asthma attacks | ✓ | ✓ | ✓ | ✓ | ✓ |
Asthma-related healthcare and other related resource use | ✓ | ✓ | ✓ | ✓ | ✓ |
Mechanistic studies | |||||
Bronchodilator response (optional) | ✓ | ||||
Skin prick testing (optional) | At any assessment | ||||
Saliva for DNA extraction (optional) | At any assessment | ||||