Summary demonstrating participant activity for the duration of the study. All study visits will occur during routine clinical follow-up visits for Fabry disease surveillance, with only two extra hospital visits for screening and implantable loop recorder (ILR) insertion. The shaded columns represent optional monitoring visits that will be centre-dependent. Adapted from SPIRIT (Standard Protocol Items Recommendations for Interventional Trials) figure (2013). Abbreviations: CMR cardiac magnetic resonance, ECG electrocardiogram, QOL quality of life.