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Table 5 Cross-sectional and stent strut-level analysis

From: Re-endothelialisation after Synergy stent and Absorb bioresorbable vascular scaffold implantation in acute myocardial infarction: COVER-AMI study

 

All patients (n = 20)

Stent diameter < 4 mma (n = 15)

 

N (%)

N (%)

p

N (%)

N (%)

p

Cross-sectional analysis (number of struts)

Absorb (229)

Synergy (191)

 

Absorb (229)

Synergy (89)

 

 Lumen area (mm2)

6.61 ±  2.12b

9.48 ±  2.50

< 0.001

6.61 ±  2.12

7.67 ±  1.67

< 0.001

 Adluminal stent/scaffold area (mm2)

8.52 ±  2.15

11.23 ±  2.72

< 0.001

8.52 ±  2.15

9.32 ± 1.74

0.002

 Endoluminal stent/scaffold area (mm2)

6.65 ±  2.01

9.72 ±  2.48

< 0.001

6.65 ±  2.01

8.00 ±  1.60

< 0.001

 Endoluminal neointimal area (mm2)

0.76 ±  0.29

0.76 ±  0.25

0.789

0.76 ±  0.29

0.73 ±  0.20

0.336

 Abluminal neointimal area + stent/scaffold strut area (mm2)

1.94 ±  0.57

1.76 ±  0.60

0.002

1.94 ±  0.57

1.65 ±  0.35

< 0.001

 Neointima

  Homogeneous

213 (93%)

162 (85%)

 

213 (93%)

79 (89%)

 

  Heterogeneous

16 (7%)

29 (15%)

0.007

16 (7%)

10 (11%)

0.214

 Cross-section with intraluminal mass

3 (1.3%)

2 (1.1%)

1.000

3 (1.3%)

2 (2.3%)

0.622

 Cross-section with malapposition area > 0

7 (3.1%)

6 (3.1%)

0.960

7 (3.1%)

0 (0.0%)

0.098

 Cross-section with uncovered struts

43 (19%)

45 (24%)

0.230

43 (19%)

19 (21%)

0.603

 Cross-section with malapposed and uncovered struts

0

1 (0.5%)

0.455

0

0 (0.0%)

 

 In stent/scaffold obstruction (%)

9.59 ± 4.81

7.01 ± 2.52

< 0.001

9.59 ±  4.81

8.12 ±  2.73

0.007

Stent strut level analysis

Absorb (2062)

Synergy (1880)

 

Absorb (2062)

Synergy (778)

 

 Uncovered struts (n, %)

47 (2.3%)

143 (7.6%)

< 0.001

47 (2.3%)

30 (3.9%)

0.021

 Malapposed struts (n, %)

7 (0.3%)

23 (1.2%)

0.001

7 (0.3%)

1 (0.1%)

0.692

 Malapposed and uncovered (n, %)

0 (0.0%)

4 (0.2%)

0.052

0 (0.0%)

0 (0.0%)

 

 Neointimal thickness per strut (mm2)

0.06 ± 0.06

0.05 ± 0.04

< 0.001

0.06 ± 0.06

0.05 ± 0.03

< 0.001

  1. aFive patients with Synergy 4-mm-diameter stent excluded
  2. bMean ± standard deviation. t test used for comparisons