Fig. 1From: A single-blind, dose-escalation, phase I study of high-fluence light-emitting diode-red light on Caucasian non-Hispanic skin: study protocol for a randomized controlled trialStudy dose-escalation flow diagram. The maximum tolerated dose (MTD) is defined as the dose level below the dose producing a dose-limiting toxicity in two or more subjects. Abbreviations: AE adverse event, HF-LED-RL High-fluence light-emitting diode-red light, VA Veterans Affairs.Back to article page