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Fig. 1 | Trials

Fig. 1

From: Rationale and protocol of the ENGAGE study: a double-blind randomized controlled preference trial using a comprehensive cohort design to measure the effect of a cognitive and leisure-based intervention in older adults with a memory complaint

Fig. 1

Illustration of the study design. ADCS-ADL-PI Alzheimer’s Disease Cooperative Study—Activities of daily living—Prevention Instrument; CLSA Canadian Longitudinal Study on Aging; (f)MRI (functional) magnetic resonance imaging; V0 Phone screening interview; V1 First visit (screening); V2 Second visit (clinical assessment); V3 Third visit (neuropsychological assessment); V4 Fourth visit (neuropsychological assessment); V5 Fifth visit (MRI; includes fMRI for a subgroup of participants); V6-29 ENGAGE Intervention sessions (24 visits); V30 4-month follow-up neuropsychological assessment; V31 4-month follow-up MRI/fMRI (for a subgroup of participants); V32 & V34 24-month follow-up neuropsychological assessment; V33 24-month follow-up clinical visit; V35 24-month follow-up MRI. X: administered during the visit; ♦: given to be completed at home by next visit

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