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Fig. 1 | Trials

Fig. 1

From: Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose—the PP100–01 for Overdose of Paracetamol (POP) trial: study protocol for a randomised controlled trial

Fig. 1

SPIRIT figure for the POP Trial. *If AEs/SAEs identified that require a full physical examination to be completed (X), NAC continued as per TOXBASE (12 h ± 30 min); 2- and 2.5-h assessments should be performed ± 15 min of the time point. PP100–01 treatment should be ± 10 min of the time point. 10- and 20-h assessments should be performed ± 30 min of the time point. ALP alkaline phosphatase, ALT alanine transaminase, APAP paracetamol/acetaminophen, BP blood pressure, ECG electrocardiogram, Hb haemoglobin, INR international normalised ratio, MCV mean cell volume, NAC N-acetylcysteine, P Pulse, WBC white blood cell

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Trials

ISSN: 1745-6215