Table 3 Weekly distribution of testing, M3EP and SIT exercise sessions across the exercise intervention

From: Mechanical suppression of osteolytic bone metastases in advanced breast cancer patients: a randomised controlled study protocol evaluating safety, feasibility and preliminary efficacy of exercise as a targeted medicine

	Monday	Tuesday	Wednesday	Thursday	Friday	Saturday	Sunday
Week 0	Baseline testing
Week 1 to Week 2	SIT	–	SIT	–	SIT	REST	REST
Week 1 to Week 2	M3EP	–	M3EP	–	M3EP	REST	REST
Week 3 to Week 12	SIT	SIT	SIT	SIT	SIT	REST	REST
Week 3 to Week 12	M3EP	SIT	M3EP	SIT	M3EP	REST	REST
Week 13	Post-Intervention Testing

Clinic exercise sessions occur on Monday, Wednesday and Friday; home isometric exercise sessions occur on Tuesday and Thursday. Spinal isometric exercises are provided at the start of all clinic exercise sessions (following a general warm up). Home-based SIT starts from week 3 onwards to enable appropriate familiarisation and training during the first 2 weeks of the programme
Abbreviations: SIT spinal isometric training (15 min), M3EP modular multi-modal exercise programme (60 min)

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ISSN: 1745-6215

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