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Table 1 Effect of tranexamic acid (TXA) on thromboembolic events in the WOMAN trial [13]

From: Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial

 

TXA (n = 10,033)

Placebo (n = 9985)

RR (95% CI)

P value

Any thromboembolic event

30 (0.3%)

34 (0.3%)

0.88 (0.54 to 1.43)

0.603

Venous events

20 (0.2%)

25 (0.3%)

0.80 (0.44 to 1.43)

0.446

DVT

3 (0.03%)

7 (0.07%)

0.43 (0.11 to 1.65)

0.203

PE

17 (0.2%)

20 (0.2%)

0.85 (0.44 to 1.61)

0.611

Arterial events

10 (0.1%)

9 (0.09%)

1.11 (0.45 to 2.72)

0.827

Myocardial infarction

2 (0.02%)

3 (0.03%)

0.66 (0.11 to 3.97)

0.651

Stroke

8 (0.08%)

6 (0.06%)

1.33 (0.46 to 3.82)

0.599

  1. CI confidence interval, DVT deep vein thrombosis, PE pulmonary embolism, RR Relative Risk