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Table 4 Weight-bands for levofloxacin (100 mg and 250 mg tablets) and resulting drug exposures

From: Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP)

Weight-bands (kg) Tablets of levofloxacin 100 (n) Tablets of levofloxacin 250 (n) Range of resulting dosages (mg/kg)
Levofloxacin 100 Levofloxacin 250
Min Max Min Max
3 4.9 0.5 0.25 10 17 13 21
5 6.9 1 0.5 14 20 18 25
7 9.9 1.5 0.75 15 21 19 27
10 11.9 2 1 17 20 21 25
12 15.9 2.5 1 16 21 16 21
16 19.9 3 1.5 15 19 19 23
20 24.9   1.5    15 19
25 29.9   2    17 20
  1. Target dosage for levofloxacin is in the range of 15–20 mg/kg
  2. Children in the placebo arm will receive the same number of tablets based on their weight-band