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Table 2 Dose and schedule of anti-TB drugs of investigational arm

From: Delamanid, linezolid, levofloxacin, and pyrazinamide for the treatment of patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (Treatment Shortening of MDR-TB Using Existing and New Drugs, MDR-END): study protocol for a phase II/III, multicenter, randomized, open-label clinical trial

Drug

Dose

Usage

Linezolid

600 mg/day for initial 2 months, then 300 mg/day

Once

Delamanid

200 mg/day

Divide in two, together with meal

Levofloxacin

750 mg (<  50 kg)

1000 mg (50–70 kg)

Once, before or after meal

Pyrazinamide

1000 mg (<  50 kg)

1500 mg (50–70 kg)

2000 mg (> 70 kg)

Once

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Trials

ISSN: 1745-6215